Preparation and Application of Nanoparticle-Oligonucleotide Aggregates

Ashley Kennedy and Dr. Nathan Green, College of Science, Northeastern State University, 3100 New Orleans St, Broken Arrow, OK 74014

Nanomaterials have recently been used to advance the field of electronics by providing more cost-effective manufacturing options. One of the lesser-known properties of nanoparticles is the ability to transfer energy, making them a prime component for building faster, more efficient electronic devices. Understanding the synthesis and functionalization of these materials will allow for the creation of nanoparticle aggregates, as well as a better understanding of nanoparticle properties and applications. The present work describes the preparation of oligonucleotide gold nanorods (GNRs) and silica nanoparticles (SNPs) for the formation of a complex nanoparticle assembly. Methods for the synthesis of SNPs included the Stöber process and amine functionalization. GNR synthesis procedures included the one-step silver-assisted seeded growth of GNRs and surface functionalization protocols. Finally, the functionalized nanoparticles were coated with oligonucleotides and mixed with a fully formed DNA origami scaffold. When combined, the resulting heteronanoparticle aggregate can be used as a unique model for non-radiatively transferring energy across the nanoscale with applications towards solar harvesting and signaling. 

Additional Abstract Information

Presenter: Ashley Kennedy

Institution: Northeastern State University

Type: Poster

Subject: Chemistry

Status: Approved

Time and Location

Session: Poster 4
Date/Time: Tue 11:00am-12:00pm
Session Number: 3511