Analysis of Stenosed Region in Artery with Its Association to Velocity and Pressure Gradient

Jordan Houseworth, Durwash Badr, Dr. Rana Zakerzadeh, Biomedical Engineering, Duquesne University, 307 Libermann Hall 600 Forbes Avenue Pittsburgh, PA 15282

Stenosis of an artery is a narrowing of the large arteries that carry blood to different regions of the body. This narrowing is usually the result of a build-up of plaque within the arteries, a condition called atherosclerosis. Stenosis can worsen over time to completely block the artery which may lead to stroke. The purpose of our research is to study flow patterns of arteries in the various shape of stenosed arteries. Symmetrical stenosed regions of three different intensities as well as an asymmetrical model will be studied.

The blood is considered as a continuum and homogeneous and is modeled using the principle of conservation of momentum and mass. The governing equations for the blood flow in arteries are solved numerically using finite volume method in ANSYS FLUENT Flow Modeling solver. Three geometries with a varying stenosis severity are modelled. In particular, severities of the stenosed artery having 30%, 60% and 90% are reduction are considered. Furthermore, an artery with an asymmetrical stenosis in which only half of the artery is blocked is observed. The velocity streamlines and the pressure contours are discussed and compared for each model.

The results show that the blockage disturbs the blood flow, and properties of the flow will change as the blood passes through the stenosed region of the artery. Due to the sudden decreased area of the artery, the velocity increased in the stenosed region. With the increased velocity, a pressure gradient across the stenosis is observed as well. It is also observed that as the severity of the stenosis increases, the stimulated pressure gradient and the velocity at the stenosed region are greatest. Moreover, the blockage is responsible for developing a turbulent flow regime for the severe stenosis of 90% blockage, which can have a damaging effect on the stenosed artery walls.

Additional Abstract Information

Presenters: Jordan Houseworth, Durwash Badr

Institution: Duquesne University

Type: Poster

Subject: Biological & Chemical Engineering

Status: Approved

Time and Location

Session: Poster 2
Date/Time: Mon 3:00pm-4:00pm
Session Number: 2529