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Tyler Dann (1), Jordan Raphel (1), Seth Gammon (2), and W. Matthew Leevy (1) (1) Department of Biological Sciences, University of Notre Dame, 100 Galvin Life Science Center, Notre Dame, IN 46556 (2) Division of Diagnostic Imaging, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030
One of the most prominent 3D printing modalities is Selective laser sintering (SLS), an additive manufacturing process in which a powdered substrate, usually polyamide (PA) or nylon, is struck with a laser to bind material together into a physical structure. PA2200, a SLS substrate that consists of nylon 12 and titanium dioxide, has popular use in industry and the commercial sphere because of its cost and durability. One use for 3D printing is to produce custom imaging phantoms, printed designs made for use in imaging machines. Photoluminescence (PL) is a phenomenon in which a material absorbs photons in the visible region, causing it to emit light afterwards. Presented here, we demonstrate the unique photoluminescent (PL) properties of native white PA2200 as it pertains to optical output in the form of a continual, phosphorescence-like emission. After analyzing luminescence and lifetime fluorescence imaging data, we concluded that the anatase phase of the titanium dioxide within PA2200 induced the enduring PL characteristics observed. Specifically, the PL characteristics of interest are the ability for PA2200 to emit PL in the near-infrared zone of the light spectrum, behavior not commonly found in 3D printed materials. These characteristics yield opportunity for advanced optical imaging applications that include lasting emission in the near-infrared zone. To demonstrate two possible research applications, this study focused on the photoluminescence imaging of PA2200 in the form of a complex, anatomically accurate rat skeleton and a novel Derenzo phantom. These two phantoms exhibit the ability of PA2200 to be used for training imaging personnel in addition to serving as a calibration tool. Overall, the optical properties of native white PA2200 originating from the addition of anatase titanium dioxide lead to an array of complex applications for producing individualized phantoms for calibration, training, and quality control that are both customizable and cost-efficient.
Presenter: Tyler Dann
Institution: Notre Dame University Of
Type: Poster
Subject: Biological & Chemical Engineering
Status: Approved
